N-Boc-4,4-difluoro-L-proline methyl ester - Names and Identifiers
Name | N-Boc-4,4-difluoro-L-proline methyl ester
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Synonyms | Methyl (S)-1-Boc-4,4-difl... N-Boc-4,4-difluoro-L-proline methyl ester N-Boc-4,4-Difluoro-L-proline methyl ester Methyl (S)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 1-tert-Butyl 2-methyl (S)-4,4-difluoropyrrolidine-1,2-dicarboxylate 1-tert-Butyl 2-methyl (2S)-4,4-difluoropyrrolidine-1,2-dicarboxylate 1-tert-butyl 2-methyl (2S)-4,4-difluoropyrrolidine-1,2-dicarboxylate Methyl 1-(tert-butoxycarbonyl)-4,4-difluoropyrrolidine-(2S)-carboxylate 1,2-Pyrrolidinedicarboxylicacid, 4,4-difluoro-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S)- 1,2-pyrrolidinedicarboxylic acid, 4,4-difluoro-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S)-
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CAS | 203866-17-5
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InChI | InChI=1/C11H17F2NO4/c1-10(2,3)18-9(16)14-6-11(12,13)5-7(14)8(15)17-4/h7H,5-6H2,1-4H3/t7-/m0/s1 |
InChIKey | RQDZKOOUQIDZOG-ZETCQYMHSA-N |
N-Boc-4,4-difluoro-L-proline methyl ester - Physico-chemical Properties
Molecular Formula | C11H17F2NO4
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Molar Mass | 265.25 |
Density | 1.22 |
Melting Point | 41-46 °C |
Boling Point | 293℃ |
Flash Point | 110°C |
Vapor Presure | 0.002mmHg at 25°C |
pKa | -8.00±0.60(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.455 |
MDL | MFCD03094918 |
N-Boc-4,4-difluoro-L-proline methyl ester - Risk and Safety
WGK Germany | 3 |
HS Code | 29339900 |
N-Boc-4,4-difluoro-L-proline methyl ester - Introduction
N-Boc-4,4-difluoro-L-proline methyl ester is an organic compound. The following is an introduction to its nature, use, formulation and safety information:
Nature:
N-Boc-4, 4-difluororo-L-proline methyl ester is a colorless or pale yellow liquid. It is relatively stable at room temperature, but decomposes at high temperatures.
Use:
N-Boc-4,4-difluoro-L-proline methyl ester is mainly used in the field of organic synthesis. It is often used as an intermediate in the synthesis of biologically active compounds. It also has applications in medicine and pesticides.
Method:
N-Boc-4, the preparation of 4-difluoro-L-proline methyl ester is generally accomplished by reacting N-Boc-4,4-difluoro-L-proline with a methylating agent (such as methyl iodide) in dichloromethane.
Safety Information:
N-Boc-4,4-difluoro-L-proline methyl ester is considered relatively safe under general operating conditions. However, it may be irritating to the skin, eyes and respiratory tract, so appropriate safety measures should be taken when using it, including wearing protective gloves and safety glasses, and make sure to operate in a well-ventilated place. In addition, it should be stored in a dry, cool place, away from open flames and oxidants. In the event of any accident, immediately take appropriate first aid measures and seek medical help.
Last Update:2024-04-09 20:52:54